Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.75 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.75 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.75 |
| ▸ | RXRA | P19793 | 1/20 | 0.73 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | CA6 | P23280 | 1/20 | 0.65 |
| ▸ | CA7 | P43166 | 1/20 | 0.65 |
| ▸ | TPMT | P51580 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.65 |
| ▸ | PDE4A | P27815 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29375753 | 1.00 | SMPD1 (0.75) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| Hydrochloric Acid SCHEMBL6586504 | 0.98 | SMPD1 (0.73) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| SCHEMBL11271923 | 0.98 | SMPD1 (0.73) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| SCHEMBL242563 | 0.94 | MRGPRX4 (0.77) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| SCHEMBL11277266 | 0.93 | MRGPRX4 (0.75) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| SCHEMBL29556736 | 0.91 | MRGPRX4 (0.62) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| SCHEMBL1600077 | 0.91 | MRGPRX4 (0.62) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| SCHEMBL4270566 | 0.90 | SMPD1 (0.73) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| SCHEMBL9236564 | 0.90 | SMPD1 (0.73) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| Hydrochloric Acid SCHEMBL10857748 | 0.89 | MRGPRX4 (0.61) | SMPD1HDAC1HDAC8HDAC6RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980152-B | Benzamide compounds with anti-tumor activity and its preparation method and application | XI'AN JIAOTONG UNIVERSITY (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-103980152-A | Benzamide compound with antitumor activity as well as preparation method and application thereof | UNIV XI AN JIAOTONG | 2014-08-13 | — | — | CN | claimed |
| EP-2279732-A2 | Compounds and compositions for delivering active agents | Emisphere Technologies, Inc. (US) | 2011-02-02 | — | — | EP | claimed |
| CN-1964939-A | Compounds and compositions for delivering active agents | EMISPHERE TECH INC (US) | 2007-05-16 | — | — | CN | claimed |
| US-20260108497-A1 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICALC., LTD. (JP) | 2026-04-23 | — | — | US | disclosed |
| EP-4678637-A1 | NOVEL FLAVONE DERIVATIVE AND USE THEREOF IN ALLEVIATING PULMONARY FIBROSIS | A-chembio Co., Ltd (KR) | 2026-01-14 | — | — | EP | disclosed |
| US-20240300913-A1 | FLAVONE DERIVATIVE AND USE THEREOF FOR IMPROVING PULMONARY FIBROSIS | A-CHEMBIO CO., LTD (KR) | 2024-09-12 | — | — | US | disclosed |
| WO-2024186175-A1 | NOVEL FLAVONE DERIVATIVE AND USE THEREOF IN ALLEVIATING PULMONARY FIBROSIS | 주식회사 에이켐바이오 | 2024-09-12 | — | — | WO | disclosed |
| US-20240148699-A1 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-05-09 | — | — | US | disclosed |
| CN-110305072-B | Compounds with phosphodiesterase 4D and acid sphingomyelinase inhibitory activity and uses thereof | 中国药科大学 | 2023-09-19 | — | — | CN | disclosed |
| US-20230115176-A1 | Complement Modulators and Related Methods | RA PHARMACEUTICALS, INC. | 2023-04-13 | — | — | US | disclosed |
| US-20220265613-A1 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-08-25 | — | — | US | disclosed |
| EP-0865439-A4 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS INC (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5629340-A | DIPHENYL FURAN COMPOUNDS | TSUMURA & CO. (JP) | 1997-05-13 | — | — | US | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0678296-A1 | VASCULARIZATION INHIBITOR AND NOVEL COMPOUND | TSUMURA & CO. (JP) | 1995-10-25 | — | — | EP | disclosed |
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |
| EP-0019081-B1 | FLAVONE DERIVATIVES, THEIR PREPARATION, THESE NOVEL AND KNOWN FLAVONES AS ANTIVIRAL AGENTS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-10-24 | — | — | EP | disclosed |
| EP-0019081-A1 | Flavone derivatives, their preparation, these novel and known flavones as antiviral agents, and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230115176-A1 | Complement Modulators and Related Methods | C5, C9, C1QBP | SMPD1 300/4885HDAC1 2943/4885HDAC8 3160/4885 |
| US-20240148699-A1 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | PDE3B, PDE4A, PDE3A | SMPD1 126/4885HDAC1 171/4885HDAC8 1129/4885 |
| US-20260108497-A1 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | PDE7B, PDE4B, PDE1B | SMPD1 197/4885HDAC1 1106/4885HDAC8 1054/4885 |
| US-20240300913-A1 | FLAVONE DERIVATIVE AND USE THEREOF FOR IMPROVING PULMONARY FIBROSIS | HGF, FN1, SMAD2 | SMPD1 3606/4885HDAC1 2640/4885HDAC8 1650/4885 |
| US-20220265613-A1 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | PDE3B, PDE4A, PDE3A | SMPD1 119/4885HDAC1 210/4885HDAC8 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.