Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 8/20 | 0.39 |
| ▸ | ESR1 | P03372 | 6/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281810 | 0.86 | ESR2 (0.36) | ESR2ESR1CYP2C9CYP3A4FFAR1 | |
| SCHEMBL11288081 | 0.84 | ESR2 (0.41) | ESR2ESR1CYP2C9CYP3A4FFAR1 | |
| SCHEMBL11277009 | 0.84 | SPHK1 (0.37) | ESR2ESR1CYP2C9CYP3A4FFAR1 | |
| SCHEMBL11282355 | 0.83 | DRD2 (0.46) | FFAR1NPC1RAB9ADGAT1 | |
| SCHEMBL11520101 | 0.81 | GRIA2 (0.47) | — | |
| SCHEMBL11520098 | 0.81 | GRIA2 (0.47) | — | |
| SCHEMBL11280039 | 0.81 | SPHK1 (0.44) | CYP2C9 | |
| SCHEMBL11287468 | 0.81 | ESR2 (0.42) | ESR2ESR1CYP2C9CYP3A4NPC1 | |
| SCHEMBL11271610 | 0.80 | DGAT1 (0.41) | NPC1RAB9ADGAT1 | |
| SCHEMBL11292668 | 0.79 | ESR2 (0.41) | ESR2ESR1CYP2C9CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022183-B1 | DERIVATIVES OF CYCLOHEXYLBIPHENYL, PROCESS FOR THEIR PREPARATION, DIELECTRICS CONTAINING THEM, AND ELECTRON OPTICAL INDICATING ELEMENTS | MERCK PATENT GmbH (DE) | 1982-06-23 | — | — | EP | disclosed |
| US-4330426-A | Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-05-18 | — | — | US | disclosed |
| EP-0022183-A2 | Derivatives of cyclohexylbiphenyl, process for their preparation, dielectrics containing them, and electron optical indicating elements | MERCK PATENT GmbH (DE) | 1981-01-14 | — | — | EP | disclosed |