Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477543 | 1.00 | HCAR2 (0.54) | HCAR2ALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL2909561 | 0.78 | KMT2A (0.73) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL2909559 | 0.78 | KMT2A (0.73) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10853322 | 0.76 | KMT2A (0.71) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10853332 | 0.76 | KMT2A (0.71) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| Piperazine SCHEMBL28235313 | 0.76 | KMT2A (0.71) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL11479548 | 0.75 | MAPT (0.74) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL11472516 | 0.75 | JUN (0.58) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL29188746 | 0.75 | ALDH1A1 (0.74) | ALDH1A1RAB9AKMT2ANPC1LMNA | |
| SCHEMBL29913474 | 0.75 | ALDH1A1 (0.74) | ALDH1A1RAB9AKMT2ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |
| US-4189484-A | Antihypertensive quinazoline derivatives | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-19 | — | — | US | disclosed |