Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662550 | 0.89 | MAOA (0.50) | KMT2AMAOACA7ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL10661812 | 0.88 | MAOA (0.52) | KMT2AMAOACA7ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL11291254 | 0.84 | CA1 (0.47) | KMT2AMEN1CA7CA1CA2 | |
| Hydrochloric Acid SCHEMBL10663034 | 0.70 | MAOA (0.47) | KMT2AMEN1MAOAALDH1A1CYP2D6 | |
| SCHEMBL10657078 | 0.70 | MTNR1B (0.51) | KMT2AMAOAALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL9352783 | 0.70 | MAOA (0.67) | KMT2AMEN1MAOACA7SMN1; SMN2 | |
| SCHEMBL8203917 | 0.69 | NR1I2 (0.80) | MAOALMNAALDH1A1MAPK1KDM4E | |
| Veradoline SCHEMBL489286 | 0.68 | MAOA (0.53) | KMT2AMAOACA7CA1CA2 | |
| Veradoline SCHEMBL29388371 | 0.68 | MAOA (0.53) | KMT2AMAOACA7CA1CA2 | |
| SCHEMBL19888927 | 0.68 | MAOA (0.97) | MAOACA7LMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051190-A2 | N-(amino(or hydroxy) phenethyl)-1,2,3,4-tetrahydroisoquinolines, precursors thereof, and methods of preparation | PENNWALT CORPORATION (US) | 1982-05-12 | — | — | EP | disclosed |