SCHEMBL1128467

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9125381	0.85	SHBG (0.48)	SHBGHTR2AKCNH2CYP3A4SMN1; SMN2
	SCHEMBL1128468	0.82	HTR2A (0.46)	HTR2A
	SCHEMBL412429	0.77	SHBG (0.50)	SHBGCYP3A4SMN1; SMN2ESR1ESR2
	SCHEMBL29065752	0.77	SHBG (0.53)	SHBGKCNH2CYP3A4SMN1; SMN2LMNA
	SCHEMBL1128449	0.75	TAAR1 (0.57)	HTR2AESR1CYP19A1ESR2TAAR1
	SCHEMBL12780419	0.75	SHBG (0.52)	SHBGHTR2AKCNH2CYP3A4SMN1; SMN2
	SCHEMBL415673	0.74	SHBG (0.50)	SHBGHTR2AKCNH2CYP3A4SMN1; SMN2
	SCHEMBL1128006	0.74	HTR2A (0.69)	SHBGHTR2ACYP3A4ESR1LMNA
	SCHEMBL4581674	0.74	SHBG (0.50)	SHBGHTR2AKCNH2CYP3A4SMN1; SMN2
	SCHEMBL12845230	0.73	LMNA (0.32)	ESR1CYP19A1ESR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.