Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11286436 | 0.99 | KDM4E (0.39) | KDM4EALDH1A1LMNAMAOBMAOA | |
| SCHEMBL11273594 | 0.85 | PSEN1 (0.42) | KDM4EALDH1A1MAOBMAOAHRH3 | |
| SCHEMBL11275713 | 0.85 | TAAR1 (0.51) | KDM4EALDH1A1LMNAMAOBMAOA | |
| Hydrochloric Acid SCHEMBL11284658 | 0.84 | TAAR1 (0.50) | KDM4EALDH1A1LMNAMAOBMAOA | |
| SCHEMBL11275830 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL11276207 | 0.82 | ALDH1A1 (0.41) | KDM4EALDH1A1LMNAMAOBMAOA | |
| SCHEMBL11282551 | 0.81 | ALDH1A1 (0.41) | KDM4EALDH1A1LMNAMAOBMAOA | |
| SCHEMBL11275711 | 0.79 | ATM (0.48) | KDM4EALDH1A1MAOBMAOA | |
| Hydrochloric Acid SCHEMBL11284635 | 0.78 | ATM (0.47) | KDM4EALDH1A1MAOBMAOA | |
| SCHEMBL11284338 | 0.77 | HIF1A (0.44) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322370-A | Polycyclic compounds | BEECHAM GROUP LIMITED (GB) | 1982-03-30 | — | — | US | claimed |
| US-4322370-A | Polycyclic compounds | BEECHAM GROUP LIMITED (GB) | 1982-03-30 | — | — | US | disclosed |