Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284686 | 0.82 | KDM4E (0.40) | ALDH1A1KDM4ELMNAL3MBTL1MAOA | |
| SCHEMBL11282551 | 0.82 | ALDH1A1 (0.41) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL11273594 | 0.82 | PSEN1 (0.42) | ALDH1A1KDM4EMAPTKMT2AMAOA | |
| SCHEMBL11278569 | 0.82 | LMNA (0.38) | ALDH1A1CA1CA2CA9KDM4E | |
| Hydrochloric Acid SCHEMBL11286436 | 0.81 | KDM4E (0.39) | ALDH1A1KDM4ELMNAL3MBTL1MAOA | |
| SCHEMBL11275830 | 0.78 | KDM4E (0.42) | ALDH1A1CA1CA2CA9KDM4E | |
| SCHEMBL11284338 | 0.78 | HIF1A (0.44) | ALDH1A1LMNA | |
| SCHEMBL11276686 | 0.78 | LMNA (0.47) | KDM4EMEN1MAPTKMT2ALMNA | |
| SCHEMBL11275711 | 0.76 | ATM (0.48) | ALDH1A1KDM4EMAOAMAOB | |
| Hydrochloric Acid SCHEMBL11284658 | 0.75 | TAAR1 (0.50) | ALDH1A1KDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322370-A | Polycyclic compounds | BEECHAM GROUP LIMITED (GB) | 1982-03-30 | — | — | US | disclosed |