Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 8/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10545926 | 1.00 | CTSL (0.34) | CTSLNAAATP53CHRM2CHRM1 | |
| SCHEMBL11286273 | 1.00 | CTSL (0.34) | CTSLNAAATP53CHRM2CHRM1 | |
| SCHEMBL10544136 | 0.85 | MAPT (0.38) | CTSLNAAATP53CHRM2CHRM1 | |
| SCHEMBL11404443 | 0.85 | MAPT (0.38) | CTSLNAAATP53CHRM2CHRM1 | |
| SCHEMBL10541790 | 0.83 | TP53 (0.31) | TP53CHRM2CHRM1CHRM3OXTR | |
| SCHEMBL10541610 | 0.80 | NAAA (0.37) | CTSLNAAATP53CHRM2CHRM1 | |
| SCHEMBL10546563 | 0.79 | NAAA (0.39) | CTSLNAAATP53ASAH1OXTR | |
| SCHEMBL11289228 | 0.78 | NAAA (0.36) | CTSLNAAACHRM2CHRM1CHRM3 | |
| SCHEMBL10542453 | 0.78 | NAAA (0.36) | CTSLNAAACHRM2CHRM1CHRM3 | |
| SCHEMBL11291088 | 0.78 | NAAA (0.36) | CTSLNAAACHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050965-A1 | Beta-lactamase inhibitory composition | Takeda Chemical Industries, Ltd. (JP) | 1982-05-05 | — | — | EP | disclosed |