Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.58 |
| ▸ | KDM4C | Q9H3R0 | 15/20 | 0.46 |
| ▸ | KDM6B | O15054 | 12/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.38 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858541 | 0.84 | KDM4C (0.47) | FOLH1KDM4CKDM6BKDM4DKDM4E | |
| SCHEMBL28079169 | 0.82 | KDM4C (0.46) | FOLH1KDM4CKDM6BKDM4DKDM4E | |
| SCHEMBL258369 | 0.82 | KDM4C (0.51) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| Hydrochloric Acid SCHEMBL5739434 | 0.81 | KDM4C (0.50) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL30465694 | 0.79 | KDM4C (0.51) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL3880004 | 0.79 | KDM4C (0.50) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL123203 | 0.79 | KDM4C (0.51) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL10751618 | 0.79 | KDM4C (0.56) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL4005290 | 0.79 | GABRP (0.55) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL6050524 | 0.78 | KDM4C (0.54) | KDM4CKDM6BKDM4DKDM4EKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053681-A1 | B-Nicotinoyloxyethyl nicotinic S-acid ester and its preparation via 2-Mercaptoethyl nicotinate | Tauro, Celesio Sonnino (IT) | 1982-06-16 | — | — | EP | disclosed |