Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.56 |
| ▸ | KDM6B | O15054 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4D | Q6B0I6 | 5/20 | 0.54 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KDM4A | O75164 | 2/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.45 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.45 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697575 | 0.88 | ALDH1A1 (0.56) | KDM4CKDM6BALDH1A1KDM4DEGLN3 | |
| SCHEMBL6387642 | 0.87 | KDM4C (0.60) | KDM4CKDM6BALDH1A1KDM4DEGLN3 | |
| SCHEMBL258224 | 0.85 | KDM6B (0.59) | KDM4CKDM6BALDH1A1KDM4DEGLN3 | |
| SCHEMBL6390426 | 0.83 | KDM4C (0.43) | KDM4CKDM6BALDH1A1KDM4DEGLN3 | |
| SCHEMBL6385274 | 0.83 | KDM4C (0.50) | KDM4CKDM6BALDH1A1KDM4DEGLN3 | |
| SCHEMBL29373730 | 0.81 | KDR (0.57) | KDM4CKDM6BALDH1A1KDM4EADRB2 | |
| SCHEMBL9858541 | 0.81 | KDM4C (0.47) | KDM4CKDM6BALDH1A1KDM4DEGLN3 | |
| SCHEMBL6257548 | 0.80 | KDM6B (0.46) | KDM4CKDM6BALDH1A1KDM4DEGLN3 | |
| SCHEMBL258369 | 0.79 | KDM4C (0.51) | KDM4CKDM6BALDH1A1KDM4DEGLN3 | |
| SCHEMBL11284708 | 0.79 | FOLH1 (0.58) | KDM4CKDM6BALDH1A1KDM4DEGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4639457-A | CARDIOTONIC AGENTS | MERCK & CO., INC. (US) | 1987-01-27 | — | — | US | disclosed |