Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | IGF1R | P08069 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287087 | 0.88 | VCP (0.40) | VCPHPGDKDM4EALDH1A1IGF1R | |
| SCHEMBL11285166 | 0.86 | KDM4E (0.39) | VCPHPGDKDM4EIGF1RTLR9 | |
| SCHEMBL11286732 | 0.82 | HTR2C (0.54) | HPGDKDM4EALDH1A1IGF1RHRH3 | |
| SCHEMBL11290046 | 0.82 | HTR2A (0.51) | HPGDKDM4EALDH1A1IGF1RNPSR1 | |
| SCHEMBL11288197 | 0.79 | HTR2A (0.51) | HPGDKDM4EALDH1A1IGF1RHTR2C | |
| SCHEMBL11384109 | 0.78 | HTR2C (0.43) | HPGDKDM4EHTR2C | |
| SCHEMBL11388666 | 0.76 | HTR2C (0.41) | KDM4EALDH1A1HTR2C | |
| SCHEMBL11397225 | 0.75 | HTR2C (0.45) | HPGDKDM4EALDH1A1POLBHTR2C | |
| SCHEMBL11399144 | 0.75 | HTR2C (0.47) | HPGDKDM4EALDH1A1POLBHTR2C | |
| SCHEMBL11288329 | 0.74 | GBA1 (0.53) | HPGDKDM4EALDH1A1HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |