Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 4/20 | 0.38 |
| ▸ | GBA1 | P04062 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | IGF1R | P08069 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285202 | 0.86 | VCP (0.37) | KDM4EVCPPOLBACHEIGF1R | |
| SCHEMBL11287087 | 0.85 | VCP (0.40) | KDM4EVCPGBA1POLBIGF1R | |
| SCHEMBL11290490 | 0.81 | HTR2C (0.53) | KDM4EVCPIGF1RHPGDSMN1; SMN2 | |
| SCHEMBL11290046 | 0.81 | HTR2A (0.51) | KDM4EGBA1HTR3AIGF1RHPGD | |
| SCHEMBL11197580 | 0.79 | ALDH1A1 (0.57) | KDM4EALOX15POLBHPGDSMN1; SMN2 | |
| SCHEMBL11288197 | 0.79 | HTR2A (0.51) | KDM4EGBA1HTR3AIGF1RHPGD | |
| SCHEMBL11203500 | 0.79 | ALDH1A1 (0.56) | KDM4EALOX15POLBHPGDSMN1; SMN2 | |
| SCHEMBL11197698 | 0.77 | ALDH1A1 (0.55) | KDM4EALOX15POLBHPGDSMN1; SMN2 | |
| SCHEMBL11289281 | 0.76 | HTR2A (0.39) | KDM4EGBA1ACHEHPGDSMN1; SMN2 | |
| SCHEMBL11288329 | 0.76 | GBA1 (0.53) | KDM4EGBA1HPGDSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |