Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.73 |
| ▸ | NPC1 | O15118 | 11/20 | 0.73 |
| ▸ | MAPT | P10636 | 9/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.73 |
| ▸ | GAA | P10253 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677954 | 0.83 | CYP1A2 (0.70) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20886106 | 0.82 | ALDH1A1 (0.59) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14350873 | 0.80 | NPC1 (0.73) | RAB9ANPC1MAPTSMN1; SMN2GAA | |
| SCHEMBL788995 | 0.79 | SMN1; SMN2 (0.81) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14451161 | 0.79 | MAPT (0.72) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8188470 | 0.78 | NPC1 (0.66) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1147541 | 0.76 | CYP1A2 (0.59) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5861384 | 0.76 | CYP1A2 (1.00) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24477522 | 0.75 | SMN1; SMN2 (0.73) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14451178 | 0.75 | MAPT (0.63) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4346088-A | ANTILIPEMICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-08-24 | — | — | US | disclosed |