SCHEMBL11285371

SCHEMBL11285371

CC(C)(C)[Si](C)(C)N1CC(NC(=O)OCc2ccccc2)C1=O

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 8/20 0.48
PREP P48147 2/20 0.45
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA1 P30542 1/20 0.44
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
CTSK P43235 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11293983 0.83 POLB (0.43) GAASMN1; SMN2
SCHEMBL10370558 0.78 NAAA (0.53) NAAAPREPALDH1A1GAACTSL
SCHEMBL9782054 0.78 NAAA (0.53) NAAAPREPALDH1A1GAACTSL
SCHEMBL15200059 0.78 NAAA (0.53) NAAAPREPALDH1A1GAACTSL
SCHEMBL15200070 0.77 NAAA (0.52) NAAAPREPALDH1A1GAACTSL
SCHEMBL10937277 0.77 NAAA (0.55) NAAAPREPALDH1A1GAACTSL
SCHEMBL9740624 0.77 NAAA (0.55) NAAAPREPALDH1A1GAACTSL
SCHEMBL11031824 0.77 TSHR (0.52) NAAAPREPALDH1A1GAACTSL
SCHEMBL11031828 0.77 TSHR (0.52) NAAAPREPALDH1A1GAACTSL
SCHEMBL10576739 0.76 NAAA (0.49) NAAAALDH1A1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0053387-A1 Method of preparing 1-sulfo-2-oxoazetidine derivatives and intermediates therefor Takeda Chemical Industries, Ltd. (JP) 1982-06-09 EP disclosed