Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PREP | P48147 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15200059 | 1.00 | NAAA (0.53) | NAAAALDH1A1GAAPREPCTSL | |
| SCHEMBL9782054 | 1.00 | NAAA (0.53) | NAAAALDH1A1GAAPREPCTSL | |
| SCHEMBL253913 | 0.86 | ALDH1A1 (0.53) | NAAAALDH1A1GAAPREPCTSL | |
| SCHEMBL11031824 | 0.85 | TSHR (0.52) | NAAAALDH1A1GAAPREPCTSL | |
| SCHEMBL10937277 | 0.85 | NAAA (0.55) | NAAAALDH1A1GAAPREPCTSL | |
| SCHEMBL9740624 | 0.85 | NAAA (0.55) | NAAAALDH1A1GAAPREPCTSL | |
| SCHEMBL11031828 | 0.85 | TSHR (0.52) | NAAAALDH1A1GAAPREPCTSL | |
| SCHEMBL15200070 | 0.83 | NAAA (0.52) | NAAAALDH1A1GAAPREPCTSL | |
| SCHEMBL8189734 | 0.83 | CASP3 (0.52) | NAAAALDH1A1GAAPREPCTSL | |
| SCHEMBL8189732 | 0.83 | CASP3 (0.52) | NAAAALDH1A1GAAPREPCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170280-B1 | NOVEL INTERMEDIATES AND PROCESS FOR THE PREPARATION OF 3-ACYLAMINO-1-HYDROXY-2-AZETIDINONES | E.R. Squibb & Sons, Inc. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0371004-A1 | [(1-Alkoxy-1-methyl)-ethoxy]-amines, their preparation and their use for the preparation of 3-acylamino-1-hydroxy-2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1990-05-30 | — | — | EP | disclosed |
| US-4633017-A | N-hydroxy protecting groups and process for the preparation of 3-acylamino-1-hydroxy-2-azetidinones | E. R. SQUIBB & SONS, INC. (US) | 1986-12-30 | — | — | US | disclosed |
| US-4581170-A | N-hydroxyl protecting groups and process and intermediates for the preparation of 3-acylamino-1-hydroxy-2-azetidinones | E. R. SQUIBB & SONS, INC. (US) | 1986-04-08 | — | — | US | disclosed |
| EP-0170280-A1 | Novel intermediates and process for the preparation of 3-acylamino-1-hydroxy-2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1986-02-05 | — | — | EP | disclosed |
| US-4533660-A | Antibacterial O-sulfated β-lactam hydroxamic acids | E. R. SQUIBB & SONS, INC. (US) | 1985-08-06 | — | — | US | disclosed |
| EP-0051381-B1 | O-SULFATED BETA-LACTAM HYDROXAMIC ACIDS | E.R. Squibb & Sons, Inc. (US) | 1985-01-30 | — | — | EP | disclosed |
| US-4337197-A | BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1982-06-29 | — | — | US | disclosed |
| EP-0051381-A1 | O-sulfated beta-lactam hydroxamic acids | E.R. Squibb & Sons, Inc. (US) | 1982-05-12 | — | — | EP | disclosed |