Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285388 | 1.00 | CYP3A4 (0.68) | CYP3A4ADRA2AL3MBTL1NPC1RAB9A | |
| Amitraz SCHEMBL2471853 | 0.81 | CYP3A4 (1.00) | CYP3A4ADRA2AL3MBTL1NPC1RAB9A | |
| Amitraz SCHEMBL1765794 | 0.81 | CYP3A4 (1.00) | CYP3A4ADRA2AL3MBTL1NPC1RAB9A | |
| Amitraz SCHEMBL3957192 | 0.81 | CYP3A4 (1.00) | CYP3A4ADRA2AL3MBTL1NPC1RAB9A | |
| Amitraz SCHEMBL37309 | 0.81 | CYP3A4 (1.00) | CYP3A4ADRA2AL3MBTL1NPC1RAB9A | |
| Amitraz SCHEMBL29370387 | 0.81 | CYP3A4 (1.00) | CYP3A4ADRA2AL3MBTL1NPC1RAB9A | |
| Amitraz SCHEMBL13346111 | 0.81 | CYP3A4 (1.00) | CYP3A4ADRA2AL3MBTL1NPC1RAB9A | |
| Amitraz SCHEMBL19312984 | 0.81 | CYP3A4 (1.00) | CYP3A4ADRA2AL3MBTL1NPC1RAB9A | |
| Amitraz SCHEMBL2471817 | 0.81 | CYP3A4 (1.00) | CYP3A4ADRA2AL3MBTL1NPC1RAB9A | |
| Amitraz SCHEMBL890417 | 0.79 | CYP3A4 (0.96) | CYP3A4ADRA2AL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356193-A | Animal feed and process | THE UPJOHN COMPANY (US) | 1982-10-26 | — | — | US | disclosed |