Amitraz

Amitraz

SCHEMBL1765794

Cc1ccc(N=CN(C)C=Nc2ccc(C)cc2C)c(C)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 1.00
ADRA2A P08913 1/20 1.00
ALDH1A1 P00352 8/20 0.46
KDM4E B2RXH2 6/20 0.46
LMNA P02545 6/20 0.46
HTT P42858 5/20 0.46
MAPT P10636 8/20 0.45
GAA P10253 4/20 0.45
POLB P06746 3/20 0.45
THRB P10828 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
ALOX15 P16050 2/20 0.45
HSD17B10 Q99714 2/20 0.45
PKM P14618 1/20 0.45
HPGD P15428 1/20 0.45
TSHR P16473 1/20 0.45
ALOX12 P18054 1/20 0.45
MPI P34949 1/20 0.45
RAB9A P51151 5/20 0.43
NPC1 O15118 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Amitraz SCHEMBL19312984 1.00 CYP3A4 (1.00) CYP3A4ADRA2AALDH1A1KDM4ELMNA
Amitraz SCHEMBL37309 1.00 CYP3A4 (1.00) CYP3A4ADRA2AALDH1A1KDM4ELMNA
Amitraz SCHEMBL2471853 1.00 CYP3A4 (1.00) CYP3A4ADRA2AALDH1A1KDM4ELMNA
Amitraz SCHEMBL3957192 1.00 CYP3A4 (1.00) CYP3A4ADRA2AALDH1A1KDM4ELMNA
Amitraz SCHEMBL2471817 1.00 CYP3A4 (1.00) CYP3A4ADRA2AALDH1A1KDM4ELMNA
Amitraz SCHEMBL13346111 1.00 CYP3A4 (1.00) CYP3A4ADRA2AALDH1A1KDM4ELMNA
Amitraz SCHEMBL29370387 1.00 CYP3A4 (1.00) CYP3A4ADRA2AALDH1A1KDM4ELMNA
Amitraz SCHEMBL890417 0.98 CYP3A4 (0.96) CYP3A4ADRA2AALDH1A1KDM4ELMNA
SCHEMBL13346107 0.91 CYP3A4 (0.83) CYP3A4ADRA2AALDH1A1KDM4ELMNA
Amitraz SCHEMBL9026554 0.91 CYP3A4 (0.83) CYP3A4ADRA2AALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 607 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119383045-A OQPSK signal demodulation and code rate estimation method under non-cooperative condition 西安空间无线电技术研究所 2025-01-28 CN claimed
CN-115960016-B Preparation method of N-methyl-bis (2, 4-xylyl iminomethyl) amine 常州齐晖药业有限公司 2024-11-12 CN claimed
EP-3677774-B1 HEAT TRANSFER ASSEMBLY EMBEDDED IN A WIND TURBINE NACELLE GENERAL ELECTRIC RENOVABLES ESPANA SL (ES) 2024-10-09 EP claimed
EP-2557922-B1 CONTROL OF ARTHROPODS IN ANIMAL ENVIRONMENTS TERRAMERA EXCO HOLDINGS LTD (CA) 2024-06-26 EP claimed
CN-117849006-A Detection device based on hydrogel coated optical fiber dislocation splicing solution acidity 天津理工大学 2024-04-09 CN claimed
US-20230180746-A1 LIQUID COMPOSITIONS COMPRISING A SUSTAINED RELEASE SYSTEM FOR INSECTICIDES TERRAMERA EXCO HOLDINGS LTD. (CA) 2023-06-15 US claimed
CN-116082664-A Preparation method of hydrogel protective layer and photo-electrochemical device capable of stabilizing 电子科技大学长三角研究院(衢州) 2023-05-09 CN claimed
CN-115960016-A Preparation method of N-methyl-bis (2, 4-xylyliminomethyl) amine 常州齐晖药业有限公司 2023-04-14 CN claimed
US-20170223962-A1 COMPOSITION AND METHODS FOR MODULATION OF THE OCTOPAMINE RECEPTOR AND ITS HOMOLOGS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2017-08-10 US claimed
WO-2016022520-A1 COMPOSITION AND METHODS FOR MODULATION OF THE OCTOPAMINE RECEPTOR AND ITS HOMOLOGS HAN KYUNG-AN (US) 2016-02-11 WO claimed
EP-0091616-B1 ACARICIDE COMPOSITIONS Montedison S.p.A. (IT) 1985-09-25 EP claimed
US-4438137-A Pesticidal compositions employing amitraz with stabilizer FBC LIMITED (GB) 1984-03-20 US claimed
EP-0091616-A1 Acaricide compositions Montedison S.p.A. (IT) 1983-10-19 EP claimed
US-4356193-A Animal feed and process THE UPJOHN COMPANY (US) 1982-10-26 US claimed
EP-0000962-B1 PESTICIDAL COMPOSITION AND METHOD OF COMBATING PESTS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1981-11-18 EP claimed
US-4239774-A MITICIDES THE BOOTS COMPANY LIMITED (GB) 1980-12-16 US claimed
US-4182772-A N,N-DI-(2,4-XYLYLIMINOMETHYL)METHYLAMINE AND A 2-CYANO-3-PHENOXYBENZYL PHENYL ACETATE, MITICIDE SHELL OIL COMPANY (US) 1980-01-08 US claimed
US-4166130-A 1,5-DI-(2,4-DIMETHYLPHENYL)-3-METHYL-1,3,5-TRIAZAPENTA-1,4 -DIENE AND CAMPHECHLOR THE BOOTS COMPANY LIMITED (GB) 1979-08-28 US claimed
US-4152454-A Insecticidal compositions comprising N'-aryl-N-methylformamidines and 3-phenoxybenzyl carboxylates FMC CORPORATION (US) 1979-05-01 US claimed
US-4104376-A O-ETHYL O-(4-(METHYLTHIO)PHENYL) S-PROPYL PHOSPHORODITHIOATE, N-METHYL-N'-2,4-XYLYL-N-(N-2,4-XYLYLFORMIMIDOYL)FORMAMIDINE MOBAY CHEMICAL CORPORATION (US) 1978-08-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170223962-A1 COMPOSITION AND METHODS FOR MODULATION OF THE OCTOPAMINE RECEPTOR AND ITS HOMOLOGS ADRA2A, ADRB2, ADRA2C CYP3A4 4570/4885ADRA2A 1/4885ALDH1A1 3389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.