Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4599441 | 0.79 | MAOB (0.51) | MAOBMRGPRX4MAOAALDH1A1KMT2A | |
| SCHEMBL1604166 | 0.77 | KCNA3 (0.46) | MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL3742274 | 0.76 | CA1 (0.45) | ALDH1A1HPGD | |
| SCHEMBL2091659 | 0.75 | DAO (0.50) | MAOBMRGPRX4DAOMAOANR4A2 | |
| SCHEMBL255033 | 0.75 | TP53 (0.59) | MAOBMRGPRX4DAO | |
| SCHEMBL29642759 | 0.75 | TP53 (0.59) | MAOBMRGPRX4DAO | |
| SCHEMBL7161162 | 0.75 | TP53 (0.46) | MAOBMRGPRX4NR4A2ALDH1A1 | |
| Fluoride SCHEMBL27290995 | 0.73 | TP53 (0.57) | MAOBMRGPRX4DAO | |
| SCHEMBL4138787 | 0.73 | CA2 (0.42) | MAOBMRGPRX4DAOKMT2A | |
| SCHEMBL778406 | 0.72 | TP53 (0.39) | MAOBMRGPRX4DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283019-A1 | GPR119 RECEPTOR AGONISTS | F. Hoffmann-La Roche AG (CH) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009141238-A1 | GPR119 RECEPTOR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-11-26 | — | — | WO | disclosed |