SCHEMBL11285641

SCHEMBL11285641

O=C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)F

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.48
HDAC3 O15379 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC10 Q969S8 1/20 0.30
HDAC11 Q96DB2 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
HDAC9 Q9UKV0 1/20 0.30
HDAC5 Q9UQL6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11284699 1.00 THRB (0.48) THRBHDAC3HDAC4HDAC1HDAC7
SCHEMBL6261463 1.00 THRB (0.48) THRBHDAC3HDAC4HDAC1HDAC7
SCHEMBL957780 0.96 THRB (0.43) THRB
SCHEMBL953593 0.91 THRB (0.62) THRB
SCHEMBL536269 0.91 THRB (0.62) THRB
SCHEMBL957654 0.91 THRB (0.62) THRB
SCHEMBL465610 0.91 THRB (0.62) THRB
SCHEMBL7782672 0.91 THRB (0.62) THRB
SCHEMBL428315 0.91 THRB (0.62) THRB
SCHEMBL7779621 0.91 THRB (0.62) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-56008342-A None JP disclosed
US-11292763-B2 Methods of making a polyfluorinated allyl ether and compounds relating to the methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-04-05 US disclosed
EP-3896052-A1 METHODS OF MAKING A POLYFLUORINATED ALLYL ETHER AND COMPOUNDS RELATING TO THE METHODS 3M Innovative Properties Co. (US) 2021-10-20 EP disclosed
EP-3625201-B1 METHODS OF MAKING A POLYFLUORINATED ALLYL ETHER AND COMPOUNDS RELATING TO THE METHODS 3M INNOVATIVE PROPERTIES CO (US) 2021-09-29 EP disclosed
EP-3625201-A2 METHODS OF MAKING A POLYFLUORINATED ALLYL ETHER AND COMPOUNDS RELATING TO THE METHODS 3M Innovative Properties Company (US) 2020-03-25 EP disclosed
CN-110770200-A Process for preparing polyfluorinated allyl ethers and compounds related thereto 3M创新有限公司 2020-02-07 CN disclosed
WO-2018211457-A2 METHODS OF MAKING A POLYFLUORINATED ALLYL ETHER AND COMPOUNDS RELATING TO THE METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-11-22 WO disclosed
US-4349650-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-14 US disclosed
US-4292449-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-09-29 US disclosed
US-4275225-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-23 US disclosed
US-4273729-A CARBONYL OR SULFONYL FLUORIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-16 US disclosed
US-4273728-A NITRILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-16 US disclosed
JP-S568342-A PRODUCTION OF FLUORINE-CONTAINING DIACID FLUORIDE ASAHI GLASS CO LTD 1981-01-28 JP disclosed