Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DBH | P09172 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | IARS1 | P41252 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | MARS1 | P56192 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11276274 | 0.88 | ALOX15 (0.53) | ALOX15KDM4EGAATUBB1HIF1A | |
| SCHEMBL11288771 | 0.87 | ALOX15 (0.48) | ALOX15KDM4EDBHGAARECQL | |
| SCHEMBL11288055 | 0.84 | ALOX15 (0.49) | ALOX15KDM4EGAAHIF1A | |
| Hydrochloric Acid SCHEMBL11277598 | 0.83 | ALOX15 (0.48) | ALOX15KDM4EGAAHIF1A | |
| SCHEMBL11279189 | 0.83 | ALOX15 (0.42) | ALOX15RECQL | |
| Hydrochloric Acid SCHEMBL11284024 | 0.83 | TSHR (0.42) | KDM4EDBHGAARECQLIARS1 | |
| SCHEMBL11282093 | 0.83 | ELANE (0.42) | KDM4EDBHGAARECQLHIF1A | |
| SCHEMBL11284400 | 0.81 | ALOX15 (0.49) | ALOX15KDM4E | |
| SCHEMBL11291256 | 0.81 | ALOX15 (0.47) | ALOX15 | |
| SCHEMBL11283315 | 0.80 | ALOX15 (0.36) | ALOX15KDM4EDBHGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |