Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | ELANE | P08246 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11276274 | 0.84 | ALOX15 (0.53) | ALOX15ALDH1A1MAPT | |
| SCHEMBL11285994 | 0.83 | ALOX15 (0.46) | ALOX15RECQL | |
| SCHEMBL11283681 | 0.81 | ALDH1A1 (0.48) | ALOX15ALDH1A1HPGDTP53POLB | |
| SCHEMBL11284006 | 0.81 | ELANE (0.46) | ALDH1A1ELANEKMT2AMEN1MAPT | |
| SCHEMBL11288055 | 0.80 | ALOX15 (0.49) | ALOX15ALDH1A1ELANE | |
| Hydrochloric Acid SCHEMBL11277598 | 0.79 | ALOX15 (0.48) | ALOX15ALDH1A1ELANE | |
| SCHEMBL11279194 | 0.78 | ALDH1A1 (0.40) | ALOX15ALDH1A1ELANEHPGDTP53 | |
| SCHEMBL11112951 | 0.78 | ALOX15 (0.43) | ALOX15ALDH1A1HPGDTP53POLB | |
| SCHEMBL11284400 | 0.77 | ALOX15 (0.49) | ALOX15ALDH1A1HPGDSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL11283476 | 0.76 | ALDH1A1 (0.36) | ALDH1A1HPGDSMN1; SMN2THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |