Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 7/20 | 0.57 |
| ▸ | BACE1 | P56817 | 6/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286012 | 1.00 | REN (0.57) | RENBACE1CTSSCTSLCTSB | |
| SCHEMBL10175603 | 0.94 | CTSS (0.58) | RENBACE1CTSSCTSLCTSB | |
| SCHEMBL11282264 | 0.94 | CTSS (0.58) | RENBACE1CTSSCTSLCTSB | |
| SCHEMBL11287800 | 0.91 | REN (0.58) | RENBACE1CTSSCTSLCTSB | |
| SCHEMBL11287796 | 0.91 | REN (0.58) | RENBACE1CTSSCTSLCTSB | |
| SCHEMBL15305530 | 0.86 | REN (0.62) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL28916808 | 0.85 | REN (0.63) | RENBACE1CTSSCTSLCTSB | |
| SCHEMBL30279290 | 0.85 | REN (0.63) | RENBACE1CTSSCTSLCTSB | |
| SCHEMBL10456411 | 0.85 | CTSS (0.69) | CTSSCTSLCTSBCTSK | |
| SCHEMBL10944784 | 0.85 | CTSS (0.69) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351828-A | N-Substituted cyclopeptide derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-28 | — | — | US | disclosed |
| US-4237045-A | N-substituted cyclopeptide derivatives and preparation thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-12-02 | — | — | US | disclosed |