Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 6/20 | 0.36 |
| ▸ | CA9 | Q16790 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11155674 | 0.94 | CA2 (0.39) | BRD4CA2CA1MMP1MMP2 | |
| SCHEMBL11281334 | 0.88 | EDNRB (0.37) | BRD4CA2CA1MMP1MMP2 | |
| SCHEMBL11155912 | 0.85 | NPC1 (0.41) | BRD4CA2CA1CA9MAPT | |
| SCHEMBL11155786 | 0.84 | POLB (0.42) | BRD4CA2CA1MMP1MMP2 | |
| SCHEMBL11286338 | 0.84 | CDK1 (0.42) | CA2CA1CA12CA9MAPT | |
| SCHEMBL11281725 | 0.82 | CA1 (0.39) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL11282581 | 0.82 | EDNRB (0.42) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL11156238 | 0.81 | KDM4E (0.49) | CA2CA1CA12CA9MAPT | |
| SCHEMBL11076516 | 0.80 | CA2 (0.49) | BRD4CA2CA1MMP1MMP2 | |
| SCHEMBL11155712 | 0.80 | KCNJ6 (0.36) | CA2CA1CA12CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339267-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | claimed |
| US-4339267-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | disclosed |