Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11155674 | 0.89 | CA2 (0.39) | ALDH1A1KDM4ENPC1MAPTCA1 | |
| SCHEMBL11155912 | 0.88 | NPC1 (0.41) | ALDH1A1KDM4ENPC1MAPTCA1 | |
| SCHEMBL11155712 | 0.87 | KCNJ6 (0.36) | ALDH1A1KDM4ENPC1MAPTNLRP3 | |
| SCHEMBL11156238 | 0.84 | KDM4E (0.49) | ALDH1A1KDM4ENPC1MAPTCA1 | |
| SCHEMBL11286256 | 0.84 | BRD4 (0.39) | ALDH1A1KDM4ENPC1MAPTNLRP3 | |
| SCHEMBL11051619 | 0.83 | CDK1 (0.49) | CDK1ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL11160117 | 0.81 | THRB (0.41) | ALDH1A1CA1CA2 | |
| SCHEMBL10846988 | 0.80 | ALDH1A1 (0.35) | ALDH1A1KDM4ENPC1MAPTNLRP3 | |
| SCHEMBL10718687 | 0.80 | MAPT (0.35) | ALDH1A1KDM4ENPC1MAPTNLRP3 | |
| SCHEMBL11044243 | 0.79 | KDM4E (0.40) | ALDH1A1KDM4ENPC1MAPTNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339267-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | claimed |
| US-4339267-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | disclosed |