Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286309 | 1.00 | DRD3 (0.44) | DRD3GRM2MAPTHTTLMNA | |
| SCHEMBL11289839 | 0.99 | DRD3 (0.45) | DRD3GRM2MAPTHTTLMNA | |
| SCHEMBL11289837 | 0.99 | DRD3 (0.45) | DRD3GRM2MAPTHTTLMNA | |
| SCHEMBL10979321 | 0.89 | MAPT (0.45) | DRD3MAPTHTTLMNAHSP90AA1 | |
| SCHEMBL10977689 | 0.89 | MAPT (0.45) | DRD3MAPTHTTLMNAHSP90AA1 | |
| SCHEMBL10977512 | 0.83 | MAPT (0.57) | DRD3MAPTHTTLMNAHSP90AA1 | |
| SCHEMBL18415114 | 0.83 | MAPT (0.57) | DRD3MAPTHTTLMNAHSP90AA1 | |
| SCHEMBL10977516 | 0.83 | MAPT (0.57) | DRD3MAPTHTTLMNAHSP90AA1 | |
| SCHEMBL11286592 | 0.77 | MAPT (0.42) | MAPTHTTLMNAHSP90AA1RAB9A | |
| SCHEMBL11286596 | 0.77 | MAPT (0.42) | MAPTHTTLMNAHSP90AA1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4354976-A | Process for the preparation of azidobenzal compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-10-19 | — | — | US | disclosed |