Methyl Carbamate

Methyl Carbamate

SCHEMBL11287154

C.COC(=O)N(c1ccccc1)c1ccccc1.COC(N)=O

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.52
ATM Q13315 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
NPSR1 Q6W5P4 4/20 0.47
CHRM4 P08173 4/20 0.46
CHRM3 P20309 4/20 0.46
CHRM5 P08912 3/20 0.44
CHRM1 P11229 3/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
ALDH1A1 P00352 4/20 0.44
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CHRM2 P08172 1/20 0.42
TSHR P16473 3/20 0.41
NPC1 O15118 1/20 0.40
POLB P06746 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3276086 0.90 L3MBTL1 (0.61) L3MBTL1ATMTDP1NPSR1CHRM4
SCHEMBL21500508 0.80 L3MBTL1 (0.50) L3MBTL1ATMTDP1NPSR1CHRM4
SCHEMBL2249329 0.79 L3MBTL1 (0.57) L3MBTL1ATMTDP1NPSR1CHRM4
SCHEMBL4107497 0.79 L3MBTL1 (0.47) L3MBTL1ATMTDP1NPSR1CHRM4
SCHEMBL27719797 0.77 RAB9A (0.55) L3MBTL1ATMTDP1NPSR1CHRM4
SCHEMBL28666537 0.77 KMT2A (0.54) L3MBTL1ATMTDP1NPSR1CHRM4
Hydrochloric Acid SCHEMBL4233000 0.77 L3MBTL1 (0.46) L3MBTL1ATMTDP1NPSR1CHRM4
SCHEMBL2092944 0.76 PTGIR (0.52) L3MBTL1ATMTDP1
SCHEMBL28216492 0.76 L3MBTL1 (0.44) L3MBTL1ATMTDP1NPSR1KMT2A
SCHEMBL29665201 0.75 TSHR (0.50) L3MBTL1ATMTDP1NPSR1CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4303794-A Separation and recovery of 4,4'-methylene dimethyl diphenyldicarbamate THE DOW CHEMICAL COMPANY (US) 1981-12-01 US claimed
US-4360476-A Method of concentrating a solution of methylene diphenyl diisocyanate in diphenyl oxide THE DOW CHEMICAL COMPANY (US) 1982-11-23 US disclosed
US-4303794-A Separation and recovery of 4,4'-methylene dimethyl diphenyldicarbamate THE DOW CHEMICAL COMPANY (US) 1981-12-01 US disclosed
US-4303794-A Separation and recovery of 4,4'-methylene dimethyl diphenyldicarbamate THE DOW CHEMICAL COMPANY (US) 1981-12-01 US disclosed
US-4303794-A Separation and recovery of 4,4'-methylene dimethyl diphenyldicarbamate THE DOW CHEMICAL COMPANY (US) 1981-12-01 US disclosed