Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053035 | 0.84 | KDM4E (0.65) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| Iodide SCHEMBL31343169 | 0.82 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL3972797 | 0.82 | ALDH1A1 (0.60) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL3972794 | 0.82 | ALDH1A1 (0.60) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL11681291 | 0.80 | ALDH1A1 (0.53) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL13877259 | 0.80 | ALDH1A1 (0.53) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL151563 | 0.80 | ALDH1A1 (0.75) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL29360167 | 0.80 | ALDH1A1 (0.75) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL29963695 | 0.80 | ALDH1A1 (0.75) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL6013329 | 0.80 | KDM4E (0.59) | KDM4EALDH1A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051668-A | Contain the dyeing composition for keratinous fibres of oxidation colorant parent and 4-hydroxy indoxyl derivative colour former and use the staining that said composition is carried out | OREAL (FR) | 1991-05-29 | — | — | CN | claimed |
| EP-2484526-B1 | INKJET RECORDING METHOD AND PRINTED MATERIAL | FUJIFILM CORP (JP) | 2017-03-22 | — | — | EP | disclosed |
| US-9523031-B2 | Organic electroluminescent device | IDEMITSU KOSAN CO., LTD. (JP) | 2016-12-20 | — | — | US | disclosed |
| US-20160263234-A1 | PRODRUGS OF PEPTIDE EPOXY KETONE PROTEASE INHIBITORS | ONYX THERAPEUTICS, INC. | 2016-09-15 | — | — | US | disclosed |
| US-9315542-B2 | Prodrugs of peptide epoxy ketone protease inhibitors | ONYX THERAPEUTICS, INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-9309283-B2 | Prodrugs of peptide epoxy ketone protease inhibitors | ONYX THERAPEUTICS, INC. (US) | 2016-04-12 | — | — | US | disclosed |
| US-20140105921-A1 | Prodrugs of Peptide Epoxy Ketone Protease Inhibitors | ONYX THERAPEUTICS, INC. | 2014-04-17 | — | — | US | disclosed |
| US-20070224448-A1 | Organic Electroluminescent Device | IDEMITSU KOSAN CO., LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
| US-20070224448-A1 | Organic Electroluminescent Device | IDEMITSU KOSAN CO., LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
| US-20070190355-A1 | Material for organic electroluminescence device and organic electroluminescence device utilizing the same | IDEMITSU KOSAN CO., LTD (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20070190355-A1 | Material for organic electroluminescence device and organic electroluminescence device utilizing the same | IDEMITSU KOSAN CO., LTD (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20070072911-A1 | Indoles and azaindoles as antiviral agents | AVOLIO SALVATORE | 2007-03-29 | — | — | US | disclosed |
| US-20070009760-A1 | Coordination metal compound, material for organic electroluminescence device, material for luminescent coating formation and organic electroluminescence device | INOUE TETSUYA | 2007-01-11 | — | — | US | disclosed |
| US-20070009760-A1 | Coordination metal compound, material for organic electroluminescence device, material for luminescent coating formation and organic electroluminescence device | INOUE TETSUYA | 2007-01-11 | — | — | US | disclosed |
| CN-1051668-A | Contain the dyeing composition for keratinous fibres of oxidation colorant parent and 4-hydroxy indoxyl derivative colour former and use the staining that said composition is carried out | OREAL (FR) | 1991-05-29 | — | — | CN | disclosed |
| US-4315068-A | CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS | RICOH CO., LTD. (JP) | 1982-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140105921-A1 | Prodrugs of Peptide Epoxy Ketone Protease Inhibitors | PREP, VIP, PEPD | KDM4E 377/4885ALDH1A1 1285/4885HSD17B10 493/4885 |
| US-20160263234-A1 | PRODRUGS OF PEPTIDE EPOXY KETONE PROTEASE INHIBITORS | PREP, VIP, PEPD | KDM4E 377/4885ALDH1A1 1285/4885HSD17B10 493/4885 |
| US-20070072911-A1 | Indoles and azaindoles as antiviral agents | IDO1, IDO2, NAT1 | KDM4E 1002/4885ALDH1A1 453/4885HSD17B10 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.