Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 17/20 | 0.57 |
| ▸ | CNR1 | P21554 | 7/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | RORA | P35398 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | RORB | Q92753 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053035 | 0.87 | KDM4E (0.65) | KDM4EALDH1A1CNR2CNR1PGR | |
| Iodide SCHEMBL31343169 | 0.86 | KDM4E (0.63) | KDM4EALDH1A1CNR2CNR1PGR | |
| SCHEMBL278343 | 0.83 | PGR (0.66) | CNR2PGRRORARORCRORB | |
| SCHEMBL29673705 | 0.82 | CNR2 (0.53) | CNR2CNR1SLC6A3 | |
| SCHEMBL28763406 | 0.82 | KDM4E (0.63) | KDM4EALDH1A1CNR2CNR1SLC6A3 | |
| SCHEMBL6575875 | 0.82 | PGR (0.64) | CNR2PGRRORARORCRORB | |
| SCHEMBL1000878 | 0.82 | PGR (0.64) | CNR2PGRRORARORCRORB | |
| SCHEMBL750975 | 0.82 | PGR (0.64) | CNR2PGRRORARORCRORB | |
| SCHEMBL6275417 | 0.82 | PGR (0.64) | CNR2PGRRORARORCRORB | |
| SCHEMBL6278388 | 0.82 | PGR (0.64) | CNR2PGRRORARORCRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115782-B2 | Process for producing aromatic compounds by Friedel-Crafts reaction | SHOWA DENKO K.K. (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20050222457-A1 | Process for producing aromatic compounds by friedel-crafts reaction | SHOWA DENKO K.K. (JP) | 2005-10-06 | — | — | US | disclosed |
| EP-1511707-A1 | PROCESS FOR PRODUCING AROMATIC COMPOUNDS BY FRIEDEL-CRAFTS REACTION | Showa Denko K.K. (JP) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003101925-A1 | PROCESS FOR PRODUCING AROMATIC COMPOUNDS BY FRIEDEL-CRAFTS REACTION | SHOWA DENKO K. K. (JP) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222457-A1 | Process for producing aromatic compounds by friedel-crafts reaction | PAH, DDC, TYR | KDM4E 330/4885ALDH1A1 769/4885CNR2 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.