Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | PNP | P00491 | 2/20 | 0.40 |
| ▸ | PYGL | P06737 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | STAT6 | P42226 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10858597 | 0.80 | PNP (0.53) | HIF1APNPPYGLKDM4EGMNN | |
| SCHEMBL4588335 | 0.75 | PNP (0.47) | HIF1APNPPYGLKDM4EGMNN | |
| SCHEMBL5574710 | 0.75 | PNP (0.47) | HIF1APNPPYGLKDM4EGMNN | |
| SCHEMBL5574698 | 0.75 | PNP (0.47) | HIF1APNPPYGLKDM4EGMNN | |
| SCHEMBL466334 | 0.75 | PNP (0.47) | HIF1APNPPYGLKDM4EGMNN | |
| SCHEMBL2778662 | 0.75 | PNP (0.47) | HIF1APNPPYGLKDM4EGMNN | |
| SCHEMBL29122970 | 0.74 | PNP (0.46) | HIF1APNPPYGL | |
| SCHEMBL30515232 | 0.73 | UMPS (0.41) | HIF1APNPPYGLKDM4ELMNA | |
| SCHEMBL10081193 | 0.73 | PNP (0.50) | HIF1APNPPYGLKDM4EGMNN | |
| SCHEMBL14365990 | 0.73 | PNP (0.50) | HIF1APNPPYGLKDM4EGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057548-A2 | 7-Beta-D-arabinofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-4-amine 5'-phosphate compounds useful as antiviral agents, pharmaceutical compositions containing the compounds, and processes for producing the compounds | WARNER-LAMBERT COMPANY (US) | 1982-08-11 | — | — | EP | disclosed |