Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | PPARD | Q03181 | 7/20 | 0.56 |
| ▸ | PPARA | Q07869 | 7/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TLR2 | O60603 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22290990 | 0.96 | AKR1B1 (0.64) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL27456937 | 0.94 | AKR1B1 (0.61) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL9105133 | 0.94 | FFAR4 (0.67) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL2579391 | 0.94 | FFAR4 (0.67) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL9119845 | 0.94 | FFAR4 (0.67) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL9107877 | 0.94 | FFAR4 (0.67) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL2577662 | 0.94 | FFAR4 (0.67) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL26679462 | 0.94 | AKR1B1 (0.54) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL14360195 | 0.92 | ALDH1A1 (0.56) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL5362865 | 0.92 | GPR84 (0.57) | FFAR4FFAR1AKR1B1GPR84PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4354981-A | Method for synthesizing dinitriles, products obtained thereby and their derivatives | ANIC, S.P.A. (IT) | 1982-10-19 | — | — | US | disclosed |
| US-4279834-A | REACTING AN ALPHA, BETA SATURATED VITRILE WITH AN ALPHA, BETA UNSATURATED NITRILE | ANIC S.P.A. (IT) | 1981-07-21 | — | — | US | disclosed |