Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25310507 | 0.84 | LMNA (0.54) | LMNAPOLBALDH1A1TP53CYP3A4 | |
| SCHEMBL1470146 | 0.83 | LMNA (0.61) | LMNAPOLBALDH1A1TP53CYP3A4 | |
| SCHEMBL14422639 | 0.82 | TP53 (0.71) | LMNAPOLBALDH1A1TP53CYP3A4 | |
| SCHEMBL15135511 | 0.81 | ALDH1A1 (0.60) | LMNAPOLBALDH1A1MGLL | |
| SCHEMBL8460521 | 0.80 | LMNA (0.57) | LMNAPOLBALDH1A1MGLL | |
| SCHEMBL14677008 | 0.80 | LMNA (0.57) | LMNAPOLBALDH1A1MGLL | |
| SCHEMBL30105359 | 0.80 | LMNA (0.57) | LMNAPOLBALDH1A1MGLL | |
| SCHEMBL12467347 | 0.80 | LMNA (0.57) | LMNAPOLBALDH1A1MGLL | |
| SCHEMBL28737825 | 0.80 | LMNA (0.57) | LMNAPOLBALDH1A1MGLL | |
| SCHEMBL6358857 | 0.79 | TP53 (0.72) | LMNAPOLBALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358459-A | Cyclopropane carboxylic acid and process for their production and use | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1982-11-09 | — | — | US | disclosed |