Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 2/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287364 | 0.90 | ALDH1A1 (0.44) | ALDH1A1TDP1CRHBPCRHR2MAPT | |
| SCHEMBL9453357 | 0.74 | SMN1; SMN2 (0.51) | ALDH1A1TDP1CRHBPCRHR2MAPT | |
| SCHEMBL11063998 | 0.73 | PTGS2 (0.43) | ALDH1A1TDP1CRHBPCRHR2MAPT | |
| SCHEMBL11598974 | 0.72 | ALDH1A1 (0.51) | ALDH1A1TDP1CRHBPCRHR2MAPT | |
| SCHEMBL28221727 | 0.70 | TDP1 (0.63) | ALDH1A1TDP1CRHBPCRHR2MAPT | |
| SCHEMBL10949109 | 0.70 | TDP1 (0.48) | ALDH1A1TDP1CRHBPCRHR2MAPT | |
| SCHEMBL28099167 | 0.69 | ALDH1A1 (0.56) | ALDH1A1TDP1CRHBPCRHR2MAPT | |
| SCHEMBL29575337 | 0.68 | TDP1 (0.71) | ALDH1A1TDP1CRHBPCRHR2MAPT | |
| SCHEMBL9444834 | 0.68 | TDP1 (0.71) | ALDH1A1TDP1CRHBPCRHR2MAPT | |
| SCHEMBL8085585 | 0.68 | MAPT (0.56) | ALDH1A1TDP1MAPTPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363917-A | SENSITIZERS FOR PHOTOCROSSLINKABLE POLYMERS; PHOTOPOLYMERIZATION INITIATORS | CIBA-GEIGY CORPORATION (US) | 1982-12-14 | — | — | US | disclosed |