Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11358034 | 0.96 | TBXAS1 (0.64) | TBXAS1KDM4EALDH1A1 | |
| SCHEMBL11282493 | 0.83 | TBXAS1 (1.00) | TBXAS1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11284471 | 0.82 | TBXAS1 (1.00) | TBXAS1ALDH1A1 | |
| SCHEMBL15883192 | 0.80 | TBXAS1 (0.64) | TBXAS1 | |
| SCHEMBL11223282 | 0.79 | TBXAS1 (0.67) | TBXAS1 | |
| SCHEMBL7444582 | 0.79 | TBXAS1 (0.67) | TBXAS1 | |
| SCHEMBL11221333 | 0.79 | TBXAS1 (0.67) | TBXAS1 | |
| SCHEMBL26528214 | 0.78 | TBXAS1 (0.57) | TBXAS1ALDH1A1 | |
| SCHEMBL11165593 | 0.78 | TBXAS1 (0.75) | TBXAS1KDM4EALDH1A1 | |
| SCHEMBL45903 | 0.75 | EGLN3 (0.62) | TBXAS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256757-A | ANTIINFLAMMATORY AND HYPOTENSIVE AGENTS; THROMBOSIS; ASTHMA; NERVOUS SYSTEM DISORDERS | ONO PHARMACEUTICAL CO., LTD. | 1981-03-17 | — | — | US | claimed |
| US-4355170-A | ANTIINFLAMMATORY, HYPERTENSIVE, ANTIASTHMATIC AGENTS, A THROMBOXANE SYNTHETASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-10-19 | — | — | US | disclosed |
| US-4256757-A | ANTIINFLAMMATORY AND HYPOTENSIVE AGENTS; THROMBOSIS; ASTHMA; NERVOUS SYSTEM DISORDERS | ONO PHARMACEUTICAL CO., LTD. | 1981-03-17 | — | — | US | disclosed |