SCHEMBL45903

SCHEMBL45903

COC(=O)CCn1ccnc1

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EGLN3 Q9H6Z9 1/20 0.62
TBXAS1 P24557 11/20 0.51
ALDH1A1 P00352 3/20 0.50
MAPT P10636 1/20 0.46
TSHR P16473 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26528214 0.90 TBXAS1 (0.57) EGLN3TBXAS1ALDH1A1MAPTTSHR
SCHEMBL15883192 0.88 TBXAS1 (0.64) EGLN3TBXAS1
SCHEMBL11223282 0.87 TBXAS1 (0.67) EGLN3TBXAS1
SCHEMBL11221333 0.87 TBXAS1 (0.67) EGLN3TBXAS1
SCHEMBL7444582 0.87 TBXAS1 (0.67) EGLN3TBXAS1
SCHEMBL47374 0.83 TBXAS1 (0.59) EGLN3TBXAS1ALDH1A1
SCHEMBL28346787 0.82 EGLN3 (0.62) EGLN3TBXAS1ALDH1A1
SCHEMBL2853083 0.81 ALDH1A1 (0.60) EGLN3ALDH1A1L3MBTL1
SCHEMBL22490369 0.81 EGLN3 (0.57) EGLN3TBXAS1ALDH1A1
SCHEMBL27782849 0.80 EGLN3 (0.56) EGLN3TBXAS1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1111237-A Preparation of amides and peptides HOFFMANN LA ROCHE (CH) 1995-11-08 CN claimed
WO-2024102434-A1 RNA COMPOSITIONS COMPRISING LIPID NANOPARTICLES OR LIPID RECONSTRUCTED NATURAL MESSENGER PACKS SENDA BIOSCIENCES, INC. (US) 2024-05-16 WO disclosed
WO-2023183616-A1 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME SENDA BIOSCIENCES, INC. (US) 2023-09-28 WO disclosed
EP-3625316-B1 DISPERSANTS, METHOD OF MAKING, AND USING SAME CHEVRON ORONITE CO (US) 2023-08-23 EP disclosed
CN-114957127-B Glutamine acyl cyclase inhibitor and preparation method and application thereof 深圳大学 2023-08-15 CN disclosed
CN-114957127-A Glutaminyl cyclase inhibitor and preparation method and application thereof 深圳大学 2022-08-30 CN disclosed
CN-110621766-B Dispersant, method of manufacture and use thereof 雪佛龙奥伦耐有限责任公司 2021-12-24 CN disclosed
US-10815446-B2 Dispersants, method of making, and using same CHEVRON ORONITE COMPANY LLC (US) 2020-10-27 US disclosed
EP-3625316-A1 DISPERSANTS, METHOD OF MAKING, AND USING SAME Chevron Oronite Company LLC (US) 2020-03-25 EP disclosed
CN-110621766-A Dispersant, method of manufacture and use thereof 雪佛龙奥伦耐有限责任公司 2019-12-27 CN disclosed
WO-2011008247-A1 FLAVIN DERIVATIVES BIORELIX, INC. (US) 2011-01-20 WO disclosed
WO-2011008247-A1 FLAVIN DERIVATIVES BIORELIX, INC. (US) 2011-01-20 WO disclosed
CN-1086701-C Chloropyridylcarbonylazoles and fungicides for agriculture and horticulture BAYER AGROCHEM KK (JP) 2002-06-26 CN disclosed
US-6384061-B1 HYDANTOIN COMPOUNDS REPRESENTED BY FORMULA (I) WHICH SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE, AND THUS CAN BE USED AS AN ANTI-CANCER AGENT, OR PHARMACEUTICALLY ACCEPTABLE SALTS LG CHEMICAL LTD. (KR) 2002-05-07 US disclosed
EP-0763530-B1 Chloropyridylcarbonyl derivatives and their use as microbiocides BAYER AGROCHEM KK (JP) 2001-12-05 EP disclosed
EP-1000036-A1 HYDANTOIN DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE LG CHEMICAL LIMITED (KR) 2000-05-17 EP disclosed
WO-1999005117-A1 HYDANTOIN DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE LG CHEMICAL LTD. (KR) 1999-02-04 WO disclosed
US-5849767-A Chloropyridylcarbonyl derivatives NIHON BAYER AGROCHEM K.K. (JP) 1998-12-15 US disclosed
CN-1147505-A Chloropyridylcarbonylazoles and fungicides for agriculture and horticulture BAYER AGROCHEM KK (JP) 1997-04-16 CN disclosed
EP-0763530-A1 Chloropyridylcarbonyl derivatives and their use as microbiocides NIHON BAYER AGROCHEM K.K. (JP) 1997-03-19 EP disclosed