Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2700487 | 0.85 | MMP2 (0.38) | CA2MMP2MMP8 | |
| SCHEMBL28090745 | 0.83 | MMP2 (0.37) | CA2MMP2MMP8 | |
| SCHEMBL28090740 | 0.83 | MMP2 (0.37) | CA2MMP2MMP8 | |
| SCHEMBL6677874 | 0.81 | TSHR (0.37) | CA2 | |
| SCHEMBL28102793 | 0.81 | MMP2 (0.35) | CA2MMP2MMP8 | |
| SCHEMBL27975036 | 0.81 | MMP2 (0.35) | CA2MMP2MMP8 | |
| SCHEMBL4585609 | 0.79 | CA2 (0.32) | CA2 | |
| SCHEMBL15211136 | 0.77 | GABBR1 (0.35) | CA2MMP2MMP8GABBR1 | |
| SCHEMBL6278517 | 0.77 | GABBR1 (0.35) | CA2MMP2MMP8GABBR1 | |
| SCHEMBL4586752 | 0.77 | GABBR1 (0.35) | CA2MMP2MMP8GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000043-B1 | BISPHOSPHINIC ACID ANHYDRIDES AND PROCESS FOR ITS PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-06 | — | — | EP | disclosed |
| US-4196141-A | Bisphosphinic acid anhydrides and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-04-01 | — | — | US | disclosed |
| EP-0000043-A1 | Bisphosphinic acid anhydrides and process for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-12-20 | — | — | EP | disclosed |