Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288281 | 1.00 | ALDH1A1 (0.50) | ALDH1A1F2ELANECTSGCTRC | |
| SCHEMBL26864515 | 0.72 | F2 (0.75) | ALDH1A1F2ELANECTSGCTRC | |
| SCHEMBL11279247 | 0.70 | LMNA (0.47) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL19240067 | 0.69 | F2 (0.39) | ALDH1A1F2ELANECTSGCTRC | |
| SCHEMBL6365438 | 0.68 | F2 (0.67) | ALDH1A1F2ELANECTSGCTRC | |
| SCHEMBL25003634 | 0.67 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MEN1KMT2AMAPT | |
| SCHEMBL11820247 | 0.67 | ALDH1A1 (0.53) | ALDH1A1HSD17B10ALOX15MEN1KMT2A | |
| SCHEMBL12927818 | 0.67 | F2 (1.00) | ALDH1A1F2ELANECTSGCTRC | |
| SCHEMBL2680644 | 0.66 | F2 (0.55) | ALDH1A1F2ELANECTSGCTRC | |
| SCHEMBL10134057 | 0.64 | F2 (0.60) | ALDH1A1F2ELANECTSGCTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4345935-A | PREEMERGENT AND POSTEMERGENT APPLICATION | ELI LILLY AND COMPANY (US) | 1982-08-24 | — | — | US | disclosed |
| US-4345936-A | Imidazoles, compositions and herbicidal method | ELI LILLY AND COMPANY (US) | 1982-08-24 | — | — | US | disclosed |