Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.77 |
| ▸ | PGR | P06401 | 7/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.67 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | AR | P10275 | 2/20 | 0.61 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.61 |
| ▸ | TNF | P01375 | 1/20 | 0.61 |
| ▸ | IL6 | P05231 | 1/20 | 0.61 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.61 |
| ▸ | GLUL | P15104 | 1/20 | 0.61 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.61 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11432971 | 0.95 | NR3C1 (0.85) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL11425650 | 0.95 | NR3C1 (0.83) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL11429938 | 0.95 | PGR (0.75) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL11431344 | 0.94 | NR3C1 (0.72) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL11287280 | 0.94 | NR3C1 (0.76) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL11430779 | 0.94 | NR3C1 (0.73) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL11439795 | 0.94 | NR3C1 (0.73) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL11429655 | 0.94 | NR3C1 (0.71) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL11431806 | 0.94 | NR3C1 (0.88) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL11438678 | 0.94 | NR3C1 (0.78) | NR3C1PGRHIF1ALMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000742-B1 | CORTICOIDS-17-ALKYLCARBONATES, PROCESS FOR THEIR PREPARATION AND PREPARATIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-12 | — | — | EP | disclosed |
| US-4242334-A | ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |
| EP-0000742-A1 | Corticoids-17-alkylcarbonates, process for their preparation and preparations containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-02-21 | — | — | EP | disclosed |