Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20201251 | 1.00 | CXCR2 (0.30) | CXCR2MAPK1TSHRSMN1; SMN2 | |
| SCHEMBL8311349 | 0.86 | — | — | |
| SCHEMBL8029568 | 0.77 | LMNA (0.38) | CXCR2TSHR | |
| SCHEMBL25420216 | 0.77 | CXCR2 (0.30) | CXCR2 | |
| SCHEMBL17803612 | 0.77 | APLNR (0.42) | — | |
| SCHEMBL4426810 | 0.77 | CXCR2 (0.31) | CXCR2 | |
| SCHEMBL16127993 | 0.75 | — | — | |
| SCHEMBL26546916 | 0.74 | — | — | |
| SCHEMBL3056682 | 0.72 | — | — | |
| SCHEMBL777755 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060955-A1 | Substituted uracils containing a 2-tetrahydropyranyl group, process for their preparation and pesticidal compositions containing them | ROUSSEL-UCLAF (FR) | 1982-09-29 | — | — | EP | disclosed |