Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11294169 | 1.00 | TAAR1 (0.51) | TAAR1NPC1RAB9AADRA1AADRA2A | |
| SCHEMBL11290845 | 0.85 | TAAR1 (0.49) | TAAR1NPC1RAB9AADRA1AADRA2A | |
| SCHEMBL11290847 | 0.85 | TAAR1 (0.49) | TAAR1NPC1RAB9AADRA1AADRA2A | |
| SCHEMBL11296641 | 0.82 | TAAR1 (0.47) | TAAR1NPC1RAB9AADRA1AADRA2A | |
| SCHEMBL11293747 | 0.81 | TAAR1 (0.46) | TAAR1NPC1RAB9AADRA1AADRA2A | |
| SCHEMBL11293744 | 0.81 | TAAR1 (0.46) | TAAR1NPC1RAB9AADRA1AADRA2A | |
| SCHEMBL11288889 | 0.81 | TAAR1 (0.51) | TAAR1NPC1RAB9AADRA1AADRA2A | |
| SCHEMBL11288890 | 0.81 | TAAR1 (0.51) | TAAR1NPC1RAB9AADRA1AADRA2A | |
| SCHEMBL11291280 | 0.77 | RAB9A (0.55) | TAAR1NPC1RAB9AADRA1AADRA2A | |
| SCHEMBL11291282 | 0.77 | RAB9A (0.55) | TAAR1NPC1RAB9AADRA1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064820-A1 | Substituted imidazole and imidazoline derivatives and their preparation and use | Farmos-Yhtyma Oy (FI) | 1982-11-17 | — | — | EP | disclosed |