Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PGD | P52209 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14747313 | 0.90 | TDP1 (0.54) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL15496479 | 0.87 | TDP1 (0.57) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL11846043 | 0.87 | TDP1 (0.62) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL4530510 | 0.80 | TDP1 (0.50) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL1116238 | 0.78 | — | — | |
| SCHEMBL6431865 | 0.77 | TDP1 (0.35) | TDP1TSHRTRPV1ALDH1A1 | |
| SCHEMBL23393101 | 0.76 | — | — | |
| SCHEMBL9425437 | 0.76 | — | — | |
| SCHEMBL840831 | 0.76 | — | — | |
| SCHEMBL28426201 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348377-A | RADIOPACITY | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1982-09-07 | — | — | US | disclosed |
| EP-0023992-B1 | DERIVATIVES OF 2,4,6-TRIODO-ISOPHTHALIC ACID, PROCESS FOR THEIR PREPARATION AND X-RAY CONTRAST AGENTS CONTAINING THEM | BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) | 1982-06-23 | — | — | EP | disclosed |
| EP-0023992-A1 | Derivatives of 2,4,6-triodo-isophthalic acid, process for their preparation and X-ray contrast agents containing them | BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) | 1981-02-18 | — | — | EP | disclosed |