Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15496479 | 0.98 | TDP1 (0.57) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL11288893 | 0.90 | TDP1 (0.46) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL4530510 | 0.89 | TDP1 (0.50) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL570534 | 0.83 | TDP1 (0.44) | TDP1TSHRTRPV1 | |
| SCHEMBL27828537 | 0.83 | TDP1 (0.44) | TDP1TSHRTRPV1 | |
| SCHEMBL14193502 | 0.78 | TDP1 (0.42) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL11846043 | 0.78 | TDP1 (0.62) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL7154355 | 0.76 | TDP1 (0.88) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL187068 | 0.76 | TDP1 (0.88) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL7146329 | 0.76 | TDP1 (0.88) | TDP1TSHRTRPV1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |