Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.72 |
| ▸ | ACHE | P22303 | 2/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | CASP7 | P55210 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11704943 | 0.98 | BCHE (0.71) | BCHELMNAADRB2CYP2D6ACHE | |
| Hydrochloric Acid SCHEMBL16553266 | 0.98 | BCHE (0.71) | BCHELMNAADRB2CYP2D6ACHE | |
| Acetic Acid SCHEMBL20972995 | 0.97 | BCHE (0.69) | BCHELMNAADRB2CYP2D6ACHE | |
| Acetic Acid SCHEMBL15392655 | 0.96 | BCHE (0.67) | BCHELMNAADRB2CYP2D6ACHE | |
| Ibuterol SCHEMBL118615 | 0.88 | BCHE (0.69) | BCHELMNAADRB2CYP2D6ACHE | |
| Ibuterol SCHEMBL11702776 | 0.87 | BCHE (0.67) | BCHELMNAADRB2CYP2D6ACHE | |
| Divabuterol SCHEMBL2109920 | 0.87 | BCHE (0.71) | BCHELMNAADRB2CYP2D6ACHE | |
| SCHEMBL10614363 | 0.86 | CYP2D6 (0.55) | BCHELMNAADRB2CYP2D6ACHE | |
| Divabuterol SCHEMBL11702548 | 0.85 | BCHE (0.69) | BCHELMNAADRB2CYP2D6ACHE | |
| Bambuterol SCHEMBL4432 | 0.84 | BCHE (1.00) | BCHELMNAADRB2CYP2D6ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190142818-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOISITON THEREOF FOR TREATMENT OF PULMONARY CONDITIONS | TECHFIELDS PHARMA CO., LTD | 2019-05-16 | — | — | US | claimed |
| CN-111499528-B | Terbutaline sulfate intermediate, preparation method thereof and method for preparing terbutaline sulfate by using terbutaline sulfate intermediate | 成都瑞特恩科技有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-111499528-A | Terbutaline sulfate intermediate, preparation method thereof and method for preparing terbutaline sulfate by using terbutaline sulfate intermediate | 成都瑞特恩科技有限公司 | 2020-08-07 | — | — | CN | disclosed |
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4011258-A | ETHANOLAMINES | AKTIEBOLAGET DRACO (SW) | 1977-03-08 | — | — | US | disclosed |
| US-3937838-A | BRONCHODILATORS, DIHYDROXYPHENYL ETHANOLAMINES | AKTIEBOLAGET DRACO (SW) | 1976-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190142818-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOISITON THEREOF FOR TREATMENT OF PULMONARY CONDITIONS | CPA3, HCAR2, HRH4 | BCHE 317/4885LMNA 2722/4885ADRB2 1823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.