⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159035 | 0.74 | — | — | |
| SCHEMBL3804136 | 0.74 | — | — | |
| SCHEMBL21316634 | 0.70 | — | — | |
| SCHEMBL755197 | 0.70 | — | — | |
| SCHEMBL14277012 | 0.67 | — | — | |
| SCHEMBL2608949 | 0.66 | ALPL (0.46) | — | |
| SCHEMBL13750213 | 0.65 | ALDH1A1 (0.36) | — | |
| SCHEMBL9376399 | 0.64 | HAO1 (0.35) | — | |
| SCHEMBL11375936 | 0.64 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL7246451 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043630-A2 | Improved process for the silylation of organic compounds with 1,1,1-trimethyl-N-(trimethylsilyl)silanamine by means of catalysis with certain nitrogen containing compounds | GIST-BROCADES N.V. (NL) | 1982-01-13 | — | — | EP | disclosed |