Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24310308 | 0.89 | KDM4E (0.50) | AGTR1MAPTTDP1ADORA1ADORA3 | |
| SCHEMBL24309613 | 0.87 | MAPT (0.44) | AGTR1MAPTTDP1ADORA1ADORA3 | |
| SCHEMBL24309283 | 0.86 | TDP1 (0.46) | AGTR1MAPTTDP1ADORA1ADORA3 | |
| SCHEMBL24309752 | 0.83 | MAPK1 (0.57) | AGTR1MAPTTDP1ADORA1ADORA3 | |
| SCHEMBL24309268 | 0.82 | BPTF (0.44) | AGTR1MAPTTDP1ADORA1ADORA3 | |
| SCHEMBL24310499 | 0.81 | AGTR1 (0.39) | AGTR1MAPTTDP1ADORA1ADORA3 | |
| SCHEMBL11026995 | 0.79 | IDH1 (0.44) | MAPTTDP1ADORA1ADORA3ADORA2A | |
| SCHEMBL24309918 | 0.79 | MAPT (0.39) | AGTR1MAPTTDP1ADORA1ADORA3 | |
| SCHEMBL24310507 | 0.77 | AGTR1 (0.38) | AGTR1MAPTTDP1ADORA1ADORA3 | |
| SCHEMBL24309748 | 0.76 | L3MBTL1 (0.38) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065226-A2 | Sulfenamides, process for their preparation, their utilisation as medicines and their preparation | BAYER AG (DE) | 1982-11-24 | — | — | EP | disclosed |