Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287234 | 0.88 | MEN1 (0.57) | MEN1CHRM2HTR1AADRA2ADRD1 | |
| SCHEMBL11292339 | 0.86 | MEN1 (0.54) | MEN1CHRM2HTR1AADRA2ADRD1 | |
| SCHEMBL11282081 | 0.81 | DRD2 (0.53) | MEN1CHRM2HTR1AADRA2ADRD1 | |
| SCHEMBL11290310 | 0.80 | DRD3 (0.56) | MEN1CHRM2HTR1AADRA2ADRD1 | |
| SCHEMBL11282805 | 0.79 | DRD2 (0.52) | MEN1CHRM2HTR1AADRA2ADRD1 | |
| SCHEMBL11285391 | 0.78 | DRD2 (0.50) | MEN1CHRM2HTR1AADRA2ADRD1 | |
| SCHEMBL11290027 | 0.77 | DRD2 (0.58) | MEN1CHRM2HTR1AADRA2ADRD1 | |
| SCHEMBL11285251 | 0.76 | DRD2 (0.53) | MEN1CHRM2HTR1AADRA2ADRD1 | |
| SCHEMBL11290212 | 0.76 | DRD2 (0.52) | DRD2TSHR | |
| SCHEMBL11288157 | 0.75 | HTR1A (0.53) | MEN1CHRM2HTR1AADRA2ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353900-A | HYPOTENSIVE, ANTIARRHYTHMIA, CARDIOTONIC, VASODILATORS | SYNTEX (U.S.A.) INC. (US) | 1982-10-12 | — | — | US | disclosed |