Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5347953 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11294593 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11294876 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL4802620 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL4796401 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11290798 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11290376 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11298231 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11298227 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11289946 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0014840-B1 | FLUORPHENYL-TRANS-CYCLOHEXANES, PROCESS FOR THEIR PREPARATION, LIQUID CRYSTALLINE DIELECTRICS CONTAINING THEM AND ELECTROOPTICAL DISPLAYING MEANS | MERCK PATENT GmbH (DE) | 1982-01-06 | — | — | EP | disclosed |
| US-4302352-A | Fluorophenylcyclohexanes, the preparation thereof and their use as components of liquid crystal dielectrics | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-11-24 | — | — | US | disclosed |
| US-4301313-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS | ELI-LILLY AND COMPANY (US) | 1981-11-17 | — | — | US | disclosed |
| US-4226887-A | P-BIPHENYLYLACETYLENE | ELI LILLY AND COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| EP-0014840-A1 | Fluorphenyl-trans-cyclohexanes, process for their preparation, liquid crystalline dielectrics containing them and electrooptical displaying means | MERCK PATENT GmbH (DE) | 1980-09-03 | — | — | EP | disclosed |
| US-3991212-A | PHENYLACETYLENE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1976-11-09 | — | — | US | disclosed |