SCHEMBL5347953

SCHEMBL5347953

CCCCCC[C@H]1CC[C@H](c2ccc(F)cc2)CC1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 11/20 0.48
CYP2C9 P11712 1/20 0.47
MAPT P10636 2/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
MEN1 O00255 1/20 0.44
MAPK1 P28482 1/20 0.44
KMT2A Q03164 1/20 0.44
GAA P10253 1/20 0.43
ESR2 Q92731 1/20 0.42
SPHK2 Q9NRA0 7/20 0.42
GRM2 Q14416 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11294593 1.00 SPHK1 (0.48) SPHK1CYP2C9MAPTALDH1A1LMNA
SCHEMBL11294876 1.00 SPHK1 (0.48) SPHK1CYP2C9MAPTALDH1A1LMNA
SCHEMBL4802620 1.00 SPHK1 (0.48) SPHK1CYP2C9MAPTALDH1A1LMNA
SCHEMBL4796401 1.00 SPHK1 (0.48) SPHK1CYP2C9MAPTALDH1A1LMNA
SCHEMBL11290798 1.00 SPHK1 (0.48) SPHK1CYP2C9MAPTALDH1A1LMNA
SCHEMBL11290376 1.00 SPHK1 (0.48) SPHK1CYP2C9MAPTALDH1A1LMNA
SCHEMBL11298231 1.00 SPHK1 (0.48) SPHK1CYP2C9MAPTALDH1A1LMNA
SCHEMBL11289256 1.00 SPHK1 (0.48) SPHK1CYP2C9MAPTALDH1A1LMNA
SCHEMBL11298227 1.00 SPHK1 (0.48) SPHK1CYP2C9MAPTALDH1A1LMNA
SCHEMBL11289946 1.00 SPHK1 (0.48) SPHK1CYP2C9MAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5279763-A Nematic liquid-crystal composition for active matrix application MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-01-18 US claimed
US-7186447-B2 Two plane parallel support plates with frame form cell, with integrated non-linear elements for switching individual picture elements on support plates, and nematic liquid crystal mixture is present in cell, having positive dielectric anisotropy and high resistivity MERCK PATENT GMBH (DE) 2007-03-06 US disclosed
US-20050196551-A1 Matrix liquid crystal display WEBER GEORG (DE) 2005-09-08 US disclosed
US-6905740-B2 The invention relates to a matrix liquid crystal display containing integrated non-linear elements and a liquid crystal mixture which has a particularly high resistivity. MERCK PATENT GMBH (DE) 2005-06-14 US disclosed
US-20030207046-A1 Matrix liquid crystal display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2003-11-06 US disclosed
US-6562419-B1 Matrix liquid crystal display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2003-05-13 US disclosed
US-6210760-B1 SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2001-04-03 US disclosed
US-6004479-A FLUOROETHERS FOR LIQUID CRYSTAL DISPLAYS AND DIELECTRICS MERCK KGAA (DE) 1999-12-21 US disclosed
EP-0394419-B2 MATRIX LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 1999-10-06 EP disclosed
US-5958290-A ELECTROOPTICAL APPARATUS WITH DIELECTRIC LIQUID CRYSTALS FOR RADIATION TRANSPARENT MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-09-28 US disclosed
EP-0414048-A2 Matrix-liquid crystal display MERCK PATENT GmbH (DE) 1991-02-27 EP disclosed
EP-0406468-A1 Nematic-liquid-crystal composition for active matrix application SHARP CORPORATION (JP) 1991-01-09 EP disclosed
EP-0394419-A1 MATRIX LIQUID CRYSTAL DISPLAY. MERCK PATENT GMBH (DE) 1990-10-31 EP disclosed
EP-0366985-A1 Super twist liquid crystal display MERCK PATENT GmbH (DE) 1990-05-09 EP disclosed
WO-1990004622-A1 SUPERTWIST LIQUID CRYSTAL DISPLAY MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-05-03 WO disclosed
WO-1990004623-A1 MATRIX LIQUID CRYSTAL DISPLAY MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-05-03 WO disclosed
EP-0365962-A1 Matrix-type liquid-crystal display MERCK PATENT GmbH (DE) 1990-05-02 EP disclosed
EP-0014840-B1 FLUORPHENYL-TRANS-CYCLOHEXANES, PROCESS FOR THEIR PREPARATION, LIQUID CRYSTALLINE DIELECTRICS CONTAINING THEM AND ELECTROOPTICAL DISPLAYING MEANS MERCK PATENT GmbH (DE) 1982-01-06 EP disclosed
US-4302352-A Fluorophenylcyclohexanes, the preparation thereof and their use as components of liquid crystal dielectrics MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1981-11-24 US disclosed
EP-0014840-A1 Fluorphenyl-trans-cyclohexanes, process for their preparation, liquid crystalline dielectrics containing them and electrooptical displaying means MERCK PATENT GmbH (DE) 1980-09-03 EP disclosed