Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5347953 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11294593 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11294876 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL4802620 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11290798 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11290376 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11298231 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11289256 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11298227 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11289946 | 1.00 | SPHK1 (0.48) | SPHK1CYP2C9MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284154-B1 | FOR LIQUID CRYSTAL CELLS, ELECTROPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2001-09-04 | — | — | US | claimed |
| EP-0502407-B1 | Nematic liquid-crystal composition for active matrix application | SHARP KK (JP) | 1996-02-07 | — | — | EP | claimed |
| US-5279763-A | Nematic liquid-crystal composition for active matrix application | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | claimed |
| US-8736794-B2 | Light emitting device | PANASONIC CORPORATION (JP) | 2014-05-27 | — | — | US | disclosed |
| US-8736794-B2 | Light emitting device | PANASONIC CORPORATION (JP) | 2014-05-27 | — | — | US | disclosed |
| US-20120236229-A1 | LIGHT EMITTING DEVICE | PANASONIC CORPORATION (JP) | 2012-09-20 | — | — | US | disclosed |
| US-8148551-B2 | Tricyclic aromatics and liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-04-03 | — | — | US | disclosed |
| US-8029696-B2 | Fused naphthalenes | MERCK PATENT GMBH (DE) | 2011-10-04 | — | — | US | disclosed |
| US-8029696-B2 | Fused naphthalenes | MERCK PATENT GMBH (DE) | 2011-10-04 | — | — | US | disclosed |
| EP-2044172-B1 | FUSED NAPHTHALENES | MERCK PATENT GMBH (DE) | 2011-06-22 | — | — | EP | disclosed |
| US-20100059711-A1 | FUSED NAPHTHALENES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-03-11 | — | — | US | disclosed |
| EP-0406468-A1 | Nematic-liquid-crystal composition for active matrix application | SHARP CORPORATION (JP) | 1991-01-09 | — | — | EP | disclosed |
| EP-0394419-A1 | MATRIX LIQUID CRYSTAL DISPLAY. | MERCK PATENT GMBH (DE) | 1990-10-31 | — | — | EP | disclosed |
| EP-0366985-A1 | Super twist liquid crystal display | MERCK PATENT GmbH (DE) | 1990-05-09 | — | — | EP | disclosed |
| WO-1990004622-A1 | SUPERTWIST LIQUID CRYSTAL DISPLAY | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-05-03 | — | — | WO | disclosed |
| WO-1990004623-A1 | MATRIX LIQUID CRYSTAL DISPLAY | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-05-03 | — | — | WO | disclosed |
| EP-0365962-A1 | Matrix-type liquid-crystal display | MERCK PATENT GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |
| EP-0014840-B1 | FLUORPHENYL-TRANS-CYCLOHEXANES, PROCESS FOR THEIR PREPARATION, LIQUID CRYSTALLINE DIELECTRICS CONTAINING THEM AND ELECTROOPTICAL DISPLAYING MEANS | MERCK PATENT GmbH (DE) | 1982-01-06 | — | — | EP | disclosed |
| US-4302352-A | Fluorophenylcyclohexanes, the preparation thereof and their use as components of liquid crystal dielectrics | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-11-24 | — | — | US | disclosed |
| EP-0014840-A1 | Fluorphenyl-trans-cyclohexanes, process for their preparation, liquid crystalline dielectrics containing them and electrooptical displaying means | MERCK PATENT GmbH (DE) | 1980-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100059711-A1 | FUSED NAPHTHALENES | CCNE2, CCNE1, F12 | SPHK1 4073/4885CYP2C9 1933/4885MAPT 3032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.