Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | BMP1 | P13497 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944820 | 0.84 | HSD17B10 (0.57) | ALDH1A1MEN1TSHRKMT2ABMP1 | |
| SCHEMBL11103793 | 0.84 | CYP3A4 (0.55) | ALDH1A1MEN1TSHRKMT2ABMP1 | |
| SCHEMBL1461671 | 0.82 | KDM4E (0.49) | ALDH1A1MEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL7625417 | 0.79 | MEN1 (0.41) | ALDH1A1MEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL10620598 | 0.78 | MEP1B (0.40) | ALDH1A1MEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL10680843 | 0.78 | KDM4E (0.40) | ALDH1A1MEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL5290521 | 0.77 | MEN1 (0.53) | ALDH1A1MEN1TSHRKMT2AKDM1A | |
| SCHEMBL4598965 | 0.75 | MEN1 (0.51) | ALDH1A1MEN1TSHRKMT2ABMP1 | |
| SCHEMBL2103383 | 0.75 | MEN1 (0.51) | ALDH1A1MEN1TSHRKMT2AKDM1A | |
| SCHEMBL2003388 | 0.74 | KMT2A (0.56) | ALDH1A1MEN1TSHRKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048045-A1 | Phenyl piperazine derivatives having antiagressive activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1982-03-24 | — | — | EP | disclosed |