Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | CHAT | P28329 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1199056 | 0.83 | TTR (0.47) | ALOX5PTGS1PTGS2TTRTRPA1 | |
| SCHEMBL4015184 | 0.81 | TUBB1 (0.34) | ALOX5PTGS1PTGS2ALDH1A1TUBB1 | |
| SCHEMBL28195017 | 0.80 | MAOB (0.62) | ALOX5TRPA1NFE2L2MAOBRELA | |
| SCHEMBL6244184 | 0.78 | TP53 (0.39) | ALOX5PTGS1PTGS2TRPA1ALDH1A1 | |
| SCHEMBL10787485 | 0.76 | MAOB (0.70) | ALOX5TRPA1NFE2L2MAOBRELA | |
| SCHEMBL93419 | 0.76 | MAOB (0.68) | ALOX5TRPA1NFE2L2MAOBCYP1A2 | |
| SCHEMBL4936136 | 0.76 | MAOB (0.68) | ALOX5TRPA1NFE2L2MAOBCYP1A2 | |
| SCHEMBL33879 | 0.76 | MAOB (0.68) | ALOX5TRPA1NFE2L2MAOBCYP1A2 | |
| SCHEMBL27481341 | 0.76 | MAOB (0.68) | ALOX5TRPA1NFE2L2MAOBCYP1A2 | |
| SCHEMBL9474707 | 0.75 | ALOX5 (0.62) | ALOX5PTGS1PTGS2TTRTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001977-B1 | SOLUBLE MULTIFUNCTIONAL LITHIUM CONTAINING INITIATORS AND THEIR USE IN A PROCESS FOR POLYMERISATION | THE DOW CHEMICAL COMPANY (US) | 1982-02-03 | — | — | EP | disclosed |
| US-4196154-A | Soluble multifunctional lithium containing initiator | THE DOW CHEMICAL COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4172100-A | 1,3-Bis[1-(4-methylphenyl)ethenyl]benzene | THE DOW CHEMICAL COMPANY (US) | 1979-10-23 | — | — | US | disclosed |
| US-4172190-A | Soluble multifunctional lithium containing initiator | THE DOW CHEMICAL COMPANY (US) | 1979-10-23 | — | — | US | disclosed |
| EP-0001977-A1 | Soluble multifunctional lithium containing initiators and their use in a process for polymerisation | THE DOW CHEMICAL COMPANY (US) | 1979-05-30 | — | — | EP | disclosed |